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Symbol Name ID |
Ilk
integrin linked kinase MGI:1195267 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | abnormal glomerular capillary morphology |
detached podocyte |
increased kidney apoptosis |
increased podocyte apoptosis |
increased urine protein level |
albuminuria |
tubulointerstitial nephritis |
abnormal kidney morphology |
abnormal podocyte morphology |
fused podocyte foot processes |
podocyte foot process effacement |
abnormal podocyte slit diaphragm morphology |
decreased podocyte number |
podocyte microvillus transformation |
abnormal renal glomerulus basement membrane morphology |
increased renal glomerulus basement membrane thickness |
abnormal renal glomerulus morphology |
expanded mesangial matrix |
glomerulosclerosis |
glomerular crescent |
renal glomerular synechia |
renal glomerulus hypertrophy |
renal interstitial fibrosis |
renal tubule atrophy |
dilated renal tubule |
abnormal ureteric bud morphology |
abnormal glomerular filtration barrier function |
kidney failure |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Ilktm1Star/Ilktm1Star Tg(NPHS2-cre)295Lbh/0 (conditional) |
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| Ilktm3Ref/Ilktm3Ref (conditional) | |||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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